The diagnosis and management of hypothalamic hamartomas in children
نویسندگان
چکیده
Hypothalamic hamartoma (HH) is a rare developmental malformation often characterized by gelastic seizures. Recent advances in treating HH have led to dramatic improvements. However, clinical protocol of HH is poorly understood. Since 2002, department Pediatric Neurosurgery of Xinhua Hospital has maintained a multidisciplinary clinical program to evaluate and treat children with HH. This program has provided the opportunity to investigate the management of HH. In this review, we summarize the clinical progress and propose a clear management principle for different HH patients.
منابع مشابه
Gelastic seizures associated with hypothalamic hamartomas. An update in the clinical presentation, diagnosis and treatment
Gelastic seizures are epileptic events characterized by bouts of laughter. Laughter-like vocalization is usually combined with facial contraction in the form of a smile. Autonomic features such as flushing, tachycardia, and altered respiration are widely recognized. Conscious state may not be impaired, although this is often difficult to asses particularly in young children. Gelastic seizures h...
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Impairments most commonly were noted in the intellectual, verbal and nonverbal memory and working memory domains, while visuospatial rotation skills were found to be the most robust. Results from Prigatano et al.’s (2004) study evaluating six children with hypothalamic hamartomas indicated significant difficulties with speech and language tasks. Deficits also were noted with learning and memory...
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